Pharmacology & ToxicologybioRxivPreprint
Genetically-encoded discovery and development of peptide-macrocycle imaging agents for PD-L1
Ratmir Derda, Vincent Albert, Matthew L. Michnik…·Frank R. Wuest
This paper develops PD-L1-targeting macrocycle imaging agents using phage-display technology without non-canonical amino acids, achieving single-digit-nanomolar potency and structural characterization.
DOI 10.64898/2026.09.11.750985