Author

Danial Yazdan

University of AlbertaORCID 0009-0006-3308-2446Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Organism:human· 1

Frequent Co-Authors

Ratmir DerdaiD· 3 shared Edward N. SchmidtiD· 2 shared Matthew Scott MacauleyiD· 2 shared A. Michael DowneyiD· 1 shared Abdelrhman Zakaria· 1 shared Alexey M. Atrazhev· 1 shared Ana GimenoiD· 1 shared Andreas Dorian· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersBiochemistry

Ratmir DerdaORCID

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3 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintSep 20, 2026

Genetically-encoded discovery and development of peptide-macrocycle imaging agents for PD-L1

Ratmir Derda, Vincent Albert, Matthew L. Michnik…·Frank R. Wuest

This paper develops PD-L1-targeting macrocycle imaging agents using phage-display technology without non-canonical amino acids, achieving single-digit-nanomolar potency and structural characterization.

DOI 10.64898/2026.09.11.750985

experimental assaydrug response / drug discovery

𝕏 PostBluesky

BiochemistryJournal of the American Chemical SocietyPeer-reviewedSep 9, 2026

Non-Carbohydrate Inhibitors of Sialic Acid-binding Immunomodulatory-type Lectin-7 (Siglec-7) Discovered from Genetically Encoded Bicyclic Peptide Libraries

Danial Yazdan, A. Michael Downey, Ana Gimeno…·Ratmir Derda

This paper discovers non-carbohydrate inhibitors of Siglec-7:GD3 interactions using BiGEL libraries and validates their potency through SPR, ELISA, and NMR.

DOI 10.1021/jacs.6c14068

proteomicsdeep learning

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BiochemistryCell chemical biologyPeer-reviewedOct 24, 2024

Multivalent DNA-encoded lectins on phage enable detecting compositional glycocalyx differences

Guilherme Meira Lima, Zeinab Jame-Chenarboo, Mirat Sojitra…·Ratmir Derda

This paper develops a phage-based liquid lectin array to detect subtle glycocalyx differences by displaying multivalent lectins on DNA-barcoded M13 phage.

15 citations

humanproteomics

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