Author

Eashant Thusoo

Center for Bioenergy InnovationORCID 0009-0001-0088-4235Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Approach:experimental assay· 2 Assay:metabolomics· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Organism:C. elegans· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Daniel Amador‐NogueziD· 3 shared David M. Stevenson· 2 shared Alex Henkel· 1 shared Alexander F. Benson· 1 shared Allison Z. WerneriD· 1 shared Andrew J. BorchertiD· 1 shared Annie JeniD· 1 shared Ashley N. Merrill· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersSystems Biology

Daniel Amador‐NoguezORCID

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3 papers

Recent·Most cited

Synthetic BiologyMetabolic EngineeringPeer-reviewedOct 1, 2026

Engineered Pseudomonas putida reconfigures metabolic fluxes to support energy demands during muconate bioproduction from lignin-related aromatics

Rebecca A. Wilkes, Patrick F. Suthers, Andrew J. Borchert…·Allison Z. Werner

This paper investigates how engineered Pseudomonas putida reconfigures metabolic fluxes to enhance muconate production from lignin-related aromatics.

DOI 10.1016/j.ymben.2026.102573

bacteria (other)metabolomics

𝕏 PostBluesky

Systems BiologymSystemsPeer-reviewedMar 25, 2026

Metabolic imbalance limits fermentation in microbes engineered for high-titer ethanol production

Bishal Dev Sharma, Eashant Thusoo, David M. Stevenson…·Daniel G. Olson

The paper identifies thermodynamic limitations in engineered microbial strains that prevent high-titer ethanol production by analyzing metabolite profiles and thermodynamic driving forces.

DOI 10.1128/msystems.00074-26

𝕏 PostBluesky

Systems BiologymBioPeer-reviewedSep 16, 2025

Thermodynamics shape the in vivo enzyme burden of glycolytic pathways

Daven B. Khana, Annie Jen, Evgenia Shishkova…·Daniel Amador‐Noguez

The paper quantifies enzyme burdens in glycolytic pathways of three bacteria, finding that thermodynamically favorable pathways require less enzymatic protein to sustain the same flux.

5 citations

E. coliC. elegans

𝕏 PostBluesky