BiochemistryNature CommunicationsPeer-reviewed
Allosteric activation of the SPRTN protease by ubiquitin maintains genome stability
Sophie Dürauer, Hyun-Seo Kang, Christian Wiebeler…·Julian Stingele
This study shows that ubiquitin activates SPRTN protease to degrade DNA-protein crosslinks, maintaining genome stability and preventing disease.
7 citations