Author

Aldwin Suryo Rahmanto

Institute of Molecular BiologyORCID 0000-0002-4593-286XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Approach:experimental assay· 1

Frequent Co-Authors

Petra BeliiD· 2 shared Abigail C Major· 1 shared Andreas InghamiD· 1 shared Andreas MundiD· 1 shared Anja GrothiD· 1 shared Christian RenziD· 1 shared Christian WiebeleriD· 1 shared Claire GuérilloniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

Petra BeliORCID

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2 papers

Recent·Most cited

Targeted disruption of linkage-specific ubiquitylation reveals a key role of K29-linked ubiquitylation in epigenome integrity

Javier Arroyo-Gomez, Matthew J Murray, Claire Guérillon, Juanjuan Wang, Ekaterina A. Isaakova, Nazaret Reverón-Gómez, Mikaela Koutrouli, Aldwin Suryo Rahmanto, Katrine Mitrofanov, Andreas Ingham, Sofie Ulfbeck Schovsbo, Katrine Weischenfeldt, Fabian Coscia, Dimitris Typas, Moritz Carl Völker-Albert, , Niels Mailand

This study uses a ubiquitin replacement strategy to show K29-linked ubiquitylation regulates SUV39H1 stability and H3K9me3 levels in human cells.

The EMBO Journal · Oct 22, 2025Peer-reviewedCell Biology

Allosteric activation of the SPRTN protease by ubiquitin maintains genome stability

Sophie Dürauer, Hyun-Seo Kang, Christian Wiebeler, Yuka Machida, Dina S Schnapka, Denitsa Yaneva, Christian Renz, Maximilian J. Götz, Pedro Weickert, Abigail C Major, Aldwin Suryo Rahmanto, Sophie M. Gutenthaler, Lena Josefine Daumann, Petra Beli, Helle D. Ulrich, , Julian Stingele

This study shows that ubiquitin activates SPRTN protease to degrade DNA-protein crosslinks, maintaining genome stability and preventing disease.

Nature Communications · Jul 21, 2025Peer-reviewedBiochemistry