Author

Samantha R Laville-Dupuy

McMaster UniversityORCID 0009-0001-2172-0184Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Christina Yi PengiD· 2 shared Ray TruantiD· 2 shared Carlos Barba BazaniD· 1 shared Elizabeth J. OsterlundiD· 1 shared J. Cousineau· 1 shared Kaitlyn DeschampsiD· 1 shared Maya KlepfishiD· 1 shared Melanie AlpaughiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

Christina Yi PengORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintNov 21, 2025

Direct Measure of DNA Damage in Huntington Disease Reveals Elevated Oxidative Genotoxic Stress and Dysfunctional DNA Repair

Carlos Barba Bazan, Samantha R Laville-Dupuy, Maya Klepfish…·Ray Truant

This study uses RADD to directly measure oxidative DNA damage in HD cells, revealing elevated DNA damage and dysfunctional DDR pathways.

DOI 10.1101/2025.11.21.689804

humanDNA methylation

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Cell BiologybioRxivPreprintMay 8, 2025

High Content System for Quantifying Mitochondrial Morphology in Patient-Derived Human Cells

Kaitlyn Deschamps, Samantha R Laville-Dupuy, Christina Yi Peng, Ray Truant

This paper develops a high-content system to quantify mitochondrial morphology in patient-derived human cells, finding Huntington Disease fibroblasts have smaller, more circular mitochondria indicating increased fission.

1 citation

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