Yangyi Zhang

The paper identifies conserved regulatory programs in placental invasion across mammals and links their dysregulation to pregnancy disorders and cancers.

The paper shows cancer disrupts gene regulatory networks by altering co-expression between genes of unicellular and multicellular origins, with changes more pronounced in advanced tumors.

The paper identifies the enzyme responsible for 5-hydroxymethyluridine (5hmU) production in dinoflagellates and shows its role in silencing transposable elements through epigenetic marking.

This study identifies m1A as the prevalent mRNA modification in dinoflagellates, showing its role in post-transcriptional regulation of translation efficiency.