Author
Peking UniversityORCID 0000-0002-7733-862XUnclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Yingke Wu, Xuejiao Xu, Nan Liang, Yunchen Xia, Andrea Y.N. Tan, Jie Yang, Xiaozhen Yang, Jackson Champer
This study evaluates Cas9 fusion proteins in Drosophila to enhance homing gene drive performance by improving HDR and reducing resistance.
bioRxiv · Oct 28, 2026 · PreprintGenetics
Xing Wang, Shang-Zhu Zhang, Siyuan Fan, Wen-Jia Zhang, Tianyi Ma, Wei Fang, Nan Liang, Yang Wu, Shi-Qi Yang, Chen‐Rui Xia, Zi-Fan Zhao, Jiuliang Zhao, Dong Xu, Xiao-Feng Zeng, Hongzhi Guan, , M-T Li
The paper constructs a single-cell atlas of cerebrospinal fluid and blood from CNS diseases, revealing immune features of NPSLE and providing a public resource for future research.
bioRxiv · Apr 2, 2026 · PreprintGenomics
Chenwang Zhang, Nan Liang, Wenbo Li, Shuai Xu, Peng Li, Wanze Ni, Na Li, Sha Han, Ningjing Ou, Haowei Bai, Yuxiang Zhang, Furong Bai, Yifan Sun, Dewei Qian, Xinjie Bu, , Chencheng Yao
This paper develops a spermatocytes-tropic mRNA-LNP delivery system to treat genetic spermatogenic disorders, showing restoration of spermatogenesis in mouse models.
Advanced Science · Feb 11, 2026Peer-reviewedMolecular Biology
This paper introduces SVEN, a hybrid sequence-oriented model that predicts tissue-specific transcriptomic impacts of structural variants across 200+ tissues and cell lines.
bioRxiv · Mar 28, 2024 · PreprintBioinformatics
Chongping Li, Ying Li, Yuci Wang, Ruixiang Meng, Xiaoyan Shi, Yangyi Zhang, Nan Liang, Hongda Huang, Yue Li, Hui Zhou, Jiawei Xu, Wenqi Xu, Hao Chen
The paper identifies the enzyme responsible for 5-hydroxymethyluridine (5hmU) production in dinoflagellates and shows its role in silencing transposable elements through epigenetic marking.
bioRxiv · Nov 30, 2023 · PreprintMolecular Biology
Chongping Li, Ying Li, Jia Guo, Yuci Wang, Xiaoyan Shi, Yangyi Zhang, Nan Liang, Jie Yuan, Jiawei Xu, Hao Chen
This study identifies m1A as the prevalent mRNA modification in dinoflagellates, showing its role in post-transcriptional regulation of translation efficiency.
bioRxiv · Nov 4, 2023 · PreprintMolecular Biology