Author

Kiera Telesnicki

Western UniversityORCID 0009-0001-2661-1956Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Amena Aktar· 2 shared Angela M. Vrieze· 2 shared Bryan HeitiD· 2 shared Paisley Cox‐Duvall· 2 shared A. Dave Nagpal· 1 shared Charles YiniD· 1 shared Dave NagpaliD· 1 shared Kasia Wodz· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Amena Aktar

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ImmunologyJournal of the American Heart AssociationPeer-reviewedOct 28, 2025

GATA2 Mediates Macrophage Proliferation During Atherosclerosis

Amena Aktar, Angela M. Vrieze, Kiera Telesnicki…·Bryan Heit

This study identifies GATA2 as a key transcription factor driving macrophage proliferation in atherosclerosis by upregulating MYB and reducing apoptosis sensitivity.

5 citations

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintJul 18, 2025

GATA2 Induces a Stem Cell-Like Transcriptional Program in Macrophages that Promotes Atherogenesis.

Amena Aktar, Angela M. Vrieze, Kiera Telesnicki…·Bryan Heit

This study shows that GATA2 upregulation in macrophages promotes atherogenesis by inducing a stem cell-like transcriptional program that impairs cholesterol efflux and phagocytosis.

DOI 10.1101/2025.07.18.665581

humanbulk RNA-seq

𝕏 PostBluesky