ImmunologyClinical ImmunologyPeer-reviewed
FASlpr gene dosage tunes the extent of lymphoproliferation and T cell differentiation in lupus
Ritu Bohat, Xiaofang Liang, Yanping Chen…·Weiyi Peng
This study shows that FASlpr gene dosage affects lymphoproliferation and T cell differentiation in lupus models, with heterozygous Faslpr leading to increased autoantibodies and Th1 cell skewing.
DOI 10.1016/j.clim.2023.109874