Author

Thomas Scarborough

Michigan State UniversityORCID 0009-0001-3488-2457Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Christina ChaniD· 2 shared Masako HaradaiD· 2 shared S. Patrick WaltoniD· 2 shared Yuki Kawai‐HaradaiD· 2 shared Jayadeep Yedla· 1 shared Nayeema Siraj· 1 shared Olivia Brennan· 1 shared SunYoung You· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 32 mutual co-author links

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2 shared papersBioengineering

Christina ChanORCID

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2 papers

Recent·Most cited

BioengineeringACS Biomaterials Science & EngineeringPeer-reviewedJun 24, 2026

Generation of Cellular Biofactories for Scalable Production of Surface-Engineered Extracellular Vesicles via CRISPR Genome Editing

Yuki Kawai‐Harada, SunYoung You, Thomas Scarborough…·Masako Harada

This study develops CRISPR-Cas9 engineered HEK293T cells for stable production of surface-engineered extracellular vesicles, showing improved consistency and scalability compared to transient transfection.

3 citationstop 5%

humanbulk RNA-seq

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BioengineeringbioRxivPreprintOct 23, 2025

A scalable filtration-based method for isolating exomeres and other nanoscale extracellular particles

Thomas Scarborough, Yuki Kawai‐Harada, Olivia Brennan…·S. Patrick Walton

This paper introduces a scalable filtration method to isolate exomeres, showing they are stable, miRNA-rich NVEPs that could improve RNA delivery.

DOI 10.1101/2025.10.23.684032

experimental assay

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