Author

Ian L. Sparks

University of Colorado AnschutzORCID 0009-0001-3779-2190Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. Marijke KeestraiD· 1 shared Brian C. RussoiD· 1 shared Daisuke MotookaiD· 1 shared Elizabeth A. NailiD· 1 shared Emily S. MelzeriD· 1 shared Enrique RojasiD· 1 shared Lauren C. Atencio· 1 shared M. Sloan SiegristiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

A. Marijke KeestraORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintMay 6, 2025

NOD2 modulates MDA5 signaling to promote coxsackievirus B3 replication

Sharon K. Kuss-Duerkop, Lauren C. Atencio, Elizabeth A. Nail…·A. Marijke Keestra

This study shows that NOD2 promotes coxsackievirus B3 replication in intestinal epithelial cells by suppressing Type 1 Interferon expression and MDA5 activation through NOD2-mediated mitophagy.

DOI 10.1101/2025.05.06.652463

mouseexperimental assay

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Molecular BiologyeLifePeer-reviewedSep 4, 2023

The cell wall polymer initiates plasma membrane partitioning in mycobacteria

Takehiro Kado, Zarina Akbary, Daisuke Motooka…·M. Sloan Siegrist

The paper shows that the cell wall polymer, not active polymerization, is critical for membrane partitioning in Mycobacterium smegmatis.

17 citations

bacteria (other)experimental assay

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