Author

Sophia Zeng

Massachusetts General HospitalORCID 0009-0001-3810-146XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Ben Kleinstiver· 1 shared Doo Eun ChoiiD· 1 shared Eun Pyo HongiD· 1 shared Hannah E. StutzmaniD· 1 shared Jacob M. LoupeiD· 1 shared Jae-Hyun JangiD· 1 shared Jong‐Min LeeiD· 1 shared Jun Wan Shin· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperGenetics

Ben Kleinstiver

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1 paper

Recent·Most cited

GeneticseLifePeer-reviewedDec 19, 2023

Base editing strategies to convert CAG to CAA diminish the disease-causing mutation in Huntington's disease

Doo Eun Choi, Jun Wan Shin, Sophia Zeng…·Jong‐Min Lee

The paper develops base editing strategies to convert CAG to CAA in Huntington's disease, reducing CAG repeat expansion and showing therapeutic potential.

9 citations

mouseexperimental assay

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