Author

Paul W. Jeffries

Washington University in St. LouisORCID 0009-0001-3838-4076Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 3

Signature Assays, Organisms & Methods

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Research Focus:GWAS / association mapping· 3 Assay:GWAS summary statistics· 3 Organism:human· 3 Approach:statistical model· 3

Frequent Co-Authors

Arpana Agrawal AiD· 3 shared Elliot C. NelsoniD· 3 shared Emma C. JohnsoniD· 3 shared Alexander Samir HatoumiD· 2 shared Dongbing LaiiD· 2 shared Henry R. KranzleriD· 2 shared Howard J. EdenbergiD· 2 shared Jared V. BalbonaiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Arpana Agrawal AORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintJun 10, 2026

Multi-ancestry genome-wide association study and meta-analysis of stimulant use disorder reveals biology and relationships to other psychiatric disorders

S L Beck, Joseph D. Deak, Daniel F. Levey…·Joel E. Gelernter

This paper conducts a multi-ancestry GWAS of stimulant use disorder, identifies 19 genome-wide significant loci, and finds genetic correlations with other psychiatric and substance use disorders.

DOI 10.64898/2026.06.05.26354997

humanGWAS summary statistics

𝕏 PostBluesky

Genetic & Genomic MedicinePsychological MedicinePeer-reviewedJan 1, 2025

Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits.

Emma C. Johnson, Dongbing Lai, Jared V. Balbona…·Arpana Agrawal A

This study performs a multi-ancestral GWAS of DSM-defined nicotine dependence, finding genetic correlations with other substance use disorders and health traits, and identifying a strong general addiction liability factor.

5 citations

humanGWAS summary statistics

𝕏 PostBluesky

Genetic & Genomic MedicinemedRxivPreprintOct 14, 2024

Examining the causal genetic effects of substance use on aging

Jared V. Balbona, Paul W. Jeffries, Aaron J. Gorelik…·Emma C. Johnson

This study identifies genetic correlations between substance use and aging indices, finding causal effects of tobacco and alcohol use on aging with alcohol effects dependent on quantity.

1 citation

humanGWAS summary statistics

𝕏 PostBluesky