Author
Medical Research Laboratory, Institute of Integrated Research, Institute of Science TokyoORCID 0009-0001-3991-8367Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Tatsuki Hori, Yoshitaka Moriwaki, Ryuichiro Ishitani
RGI-Toolkit enables controllable biomolecular structure prediction by integrating experimental restraints into diffusion models without retraining.
Yuma Matsuoka, Hajime Inoue, Tatsuki Hori…·Shigeki Kiyonaka
The paper introduces an off-target-free chemogenetic platform to study GPCR functions, demonstrating its application on the adenosine A2A receptor and showing its generalizability to other class A GPCRs.
Tatsuki Hori, Yoshitaka Moriwaki, Ryuichiro Ishitani
This paper introduces a distance-restraint-guided diffusion model to sample protein conformational changes and ligand dissociation pathways, achieving uniform coverage and high structural quality.