Deepak Kumar Choudhary

This study shows CRISPR-Cas targeting in Haloferax volcanii increases within-species mating and recombination, promoting gene exchange while limiting inter-species transfer.

This study shows a TIR-SAVED effector can act independently as an antiviral defense, clearing viruses without its cyclase partner and using a host-produced second messenger.

This study shows that the archaeal CBASS system H-CBASS2 protects against both lytic and chronic viruses by depleting NAD+, with different kinetics depending on infection type.