Diti Patel

Matching cell masks between two-photon calcium images and thick, expanded EASI-FISH volumes recovers molecular identity for 72% (slice) to 83% (in vivo) of imaged neurons on conventional microscopes.

QuadCleave provides an inexpensive, efficient method to validate G4-forming sequences and assess their repeat counts using two enzymes, with application to C9ORF72 in ALS and FTD.