Niklas Gesmar Madsen

This paper demonstrates the production of galantamine in yeast through pathway engineering and optimization, achieving a 173-fold improvement over the parental strain.

This study develops biosensors for MIAs and identifies metabolic engineering hits to enhance MIA production in yeast.

ProteusAI is an open-source platform that streamlines ML-guided protein design and engineering, improving proteins and enzymes efficiently within the DBTL cycle.

The paper introduces a model called CSNN that uses network homophily to improve in-distribution predictions of drug-target interactions for human GPCRs.

This paper designs a polycarbonate hydrolase enzyme from scratch, demonstrating its ability to degrade polycarbonate not achievable by natural enzymes.