Rachel L. Pennie

This study uses spatial transcriptomics to analyze gene expression in lung adenocarcinoma morphologies, revealing plasticity and gene expression trajectories linked to lethal growth patterns.

This study shows that increased mRNA translation delays lung adenocarcinoma initiation and creates a vulnerability to MEK inhibitors in KRAS-driven tumors.

PixlMap is a deep learning method for cellular phenotyping in multiplex immunofluorescence images that uses nuclear segmentation alone to classify cells without requiring full cell boundaries.