Molecular BiologyNucleic Acids ResearchPeer-reviewed
An enhanced Eco1 retron editor enables precision genome engineering in human cells without double-strand breaks
Matthew A. Cattle, Lauren C Aguado, Samantha Sze…·John Thomas Poirier
This paper enhances the Eco1 retron editor for precise genome editing in human cells by improving ncRNA stability and reducing sgRNA extension, achieving editing without double-strand breaks.
6 citations