Author

Mélanie Lopes

InsermORCID 0009-0001-5665-4826Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

C. Bruce VerchereiD· 1 shared Clara Pirlian· 1 shared Clément Quintard· 1 shared Delphine FreidaiD· 1 shared Emily TubbsiD· 1 shared Jorden Gill· 1 shared Josef Martin PenningeriD· 1 shared Julia Sabatier· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

C. Bruce VerchereORCID

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2 papers

Recent·Most cited

BioengineeringCell ReportsPeer-reviewedOct 1, 2025

Fusion of blood vessel organoids with human pancreatic islets improves insulin response over time.

Emily Tubbs, Mahira Mehanović, Mélanie Lopes…·Xavier Gidrol

This study fuses blood vessel organoids with human pancreatic islets, showing improved insulin response over time in two donors.

16 citationstop 2%

humanorganoid / primary culture

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Cell BiologybioRxivPreprintJul 7, 2025

Elevations in plasma proinsulin predict the development of diabetes in NOD mice

Vriti Bhagat, Jorden Gill, Mélanie Lopes, C. Bruce Verchere

This study shows that elevated plasma proinsulin and PI:C ratios predict diabetes onset in NOD mice and correlate with reduced beta cell Pc1/3 expression.

DOI 10.1101/2025.07.07.663576

mouseproteomics

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