Author

Jonathan Eisert

Goethe University FrankfurtORCID 0009-0001-6850-5908Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:protein sequence· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Ivan ĐikićiD· 2 shared Alberto CristianiiD· 1 shared Ansgar A. WegeneriD· 1 shared Arghya DuttaiD· 1 shared Borna MarkusiciD· 1 shared Chiara BechtiD· 1 shared Cosmin TudoseiD· 1 shared Eva-Maria Leibrock· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioinformatics

Ivan ĐikićORCID

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2 papers

Recent·Most cited

BioinformaticsNature CommunicationsPeer-reviewedDec 25, 2025

Multi-scale classification decodes the complexity of the human E3 ligome

Arghya Dutta, Alberto Cristiani, Siddhanta V. Nikte…·Ramachandra M. Bhaskara

This paper constructs a comprehensive annotated dataset of human E3 ligases and uses a hierarchical classification framework to analyze their functional and structural relationships.

14 citationstop 4%

humanprotein structure

𝕏 PostBluesky

BiophysicsbioRxivPreprintJan 18, 2024

Engineering CRBN for rapid identification of next generation binders

H. J. Bailey, Jonathan Eisert, Joshua Vollrath…·Ivan Đikić

This paper introduces a new CRBN construct for efficient binder discovery, showing it outperforms existing constructs in binding and production, and applies it to identify potent CRBN binders from a large compound library.

3 citations

humanexperimental assay

𝕏 PostBluesky