Author

Priscilla Villalona

Pennsylvania State UniversityORCID 0009-0001-7862-7909Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

C. Denise OkaforiD· 2 shared Addison Barbe· 1 shared Arumay BiswasiD· 1 shared Crawford Joseph Frisbie· 1 shared Jill Magafas· 1 shared Jordan A. Wenning· 1 shared Namita DubeiD· 1 shared Sabab Hasan KhaniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

C. Denise OkaforORCID

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2 papers

Recent·Most cited

BiochemistryChemBioChemPeer-reviewedSep 10, 2026

A novel SXXLF motif in the FXR N-terminal domain mediates coregulator and interdomain interactions

Priscilla Villalona, Thilini Pulahinge, Tracy Yu…·C. Denise Okafor

This study identifies a novel SXXLF motif in the FXR N-terminal domain that mediates interactions with coregulators and the ligand binding domain, modulating transcriptional activity.

DOI 10.1002/cbic.202500967

humanexperimental assay

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BiochemistryJournal of Molecular BiologyPeer-reviewedSep 25, 2024

Nuclear receptor interdomain communication is mediated by the hinge with ligand specificity

Saurov Hazarika, Tracy Yu, Arumay Biswas…·C. Denise Okafor

This study uses computational and experimental methods to show that the hinge region of FXR mediates ligand-induced interdomain communication.

8 citations

humanstructural biology

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