Namita Dube

Whole genome sequencing-based multi-locus association mapping for kernel iron, zinc and protein content in groundnut

This study uses whole genome sequencing and GWAS to identify genetic markers associated with kernel iron, zinc, and protein content in groundnut, aiding in breeding for improved nutritional traits.

Mapping Fusarium Wilt and Sterility Mosaic Disease Resistance-Associated Genomic Regions and Haplotype Variants in Pigeonpea

This study identifies genomic regions and haplotypes associated with resistance to fusarium wilt and sterility mosaic disease in pigeonpea using GWAS and KASP validation.

Modeling Alternative Conformational States in CASP16

This paper evaluates methods for modeling multi-state protein and RNA systems in CASP16, finding improved accuracy for some targets but persistent challenges in capturing structural details for others.

Dissecting genomic regions and candidate genes for pod borer resistance and component traits in pigeonpea minicore collection

This study identifies significant marker-trait associations and candidate genes for pod borer resistance and related traits in pigeonpea using GWAS and field evaluations.

InDels in an intronic region of gene Ccsmd04 coding for dormancy/auxin-associated protein controls sterility mosaic disease resistance in pigeonpea

The paper identifies InDels in the Ccsmd04 gene associated with sterility mosaic disease resistance in pigeonpea using QTL-seq and validates them as diagnostic markers.

Genomic analysis reveals the interplay between ABA-GA in determining dormancy duration in groundnut

The paper identifies genomic markers associated with seed dormancy in groundnut and develops SNP markers for breeding improved cultivars with controlled dormancy periods.

Simulations reveal unique roles for the FXR hinge in the FXR-RXR nuclear receptor heterodimer

The paper uses simulations to study the FXR-RXR heterodimer's structure and shows the hinge's role in DNA binding and interdomain allostery.

Memorization Bias Impacts Modeling of Alternative Conformational States of Symmetric Solute Carrier Membrane Proteins with Methods from Deep Learning

The paper assesses how memorization affects AlphaFold's ability to model multiple conformational states of symmetric SLC proteins and proposes a combined ESM-template-based method to improve this.

Identification of Antimalarial Compounds that Inhibit Apicomplexan AP2 Proteins in the Human Malaria Parasite Plasmodium falciparum

The paper identifies antimalarial compounds that inhibit ApiAP2 proteins in Plasmodium falciparum by screening small molecules against the AP2-EXP domain and validating their effects on parasite gene regulation and growth.