Sama Shamloo

The paper identifies GAPDH as a non-canonical RNA-binding protein in AML that stabilizes transcripts and promotes translation, revealing its role in tumor proliferation.

The paper identifies lncRNAs involved in melanoma growth and metastasis using CRISPR-inhibition screens and validates their functional roles.

This study introduces a dual CRISPRi system to target lncRNAs in melanoma cells, enabling synthetic lethal screening to identify cancer-specific lncRNA interactions for therapeutic strategies.