Author

Pin‐Ru Chen

National Tsing Hua UniversityORCID 0009-0001-8653-2651Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1

Frequent Co-Authors

Chia-Chen Chien· 1 shared Guang-Shen Chiu· 1 shared Hsing-Jien Kung· 1 shared Hui‐Chun ChengiD· 1 shared Kai‐Ti LiniD· 1 shared Lily Hui-Ching WangiD· 1 shared Lu-Hai WangiD· 1 shared Min-Chen Tsou· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Chia-Chen Chien

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1 paper

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedAug 28, 2024

Hydrogen Sulfide Coordinates Glucose Metabolism Switch through Destabilizing Tetrameric Pyruvate Kinase M2

Rong‐Hsuan Wang, Pin‐Ru Chen, Yue-Ting Chen…·Kai‐Ti Lin

This study shows hydrogen sulfide destabilizes PKM2 tetramer through sulfhydration at cysteine 326, rewiring glucose metabolism and inhibiting tumor growth.

49 citationstop 2%

humanproteomics

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