Author

Patrick Gizzi

Centre National de la Recherche ScientifiqueORCID 0009-0001-9407-6916Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Arnaud DuchoniD· 1 shared Claire ChevalieriD· 1 shared Claire Gavériaux‐RuffiD· 1 shared Dominique BonnetiD· 1 shared François DaubeufiD· 1 shared Frédéric SimoniniD· 1 shared Glenn-Marie Le Coz· 1 shared Julien DairouiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Arnaud DuchonORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintMay 16, 2026

LONG-TERM NEURODEVELOPMENTAL AND COGNITIVE OUTCOMES FOLLOWING PRENATAL INHIBITION OF DYRK1A BY LEUCETTINE L41 IN MOUSE MODELS OF DOWN SYNDROME

Arnaud Duchon, Claire Chevalier, Patrick Gizzi…·Yann Hérault

This study investigates the effects of prenatal DYRK1A inhibition with Leucettine L41 in DS mouse models, showing lasting cognitive and gene expression improvements with model-specific outcomes.

DOI 10.64898/2026.05.13.724917

mouseexperimental assay

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Pharmacology & ToxicologybioRxivPreprintFeb 20, 2026

A metabolically resistant spexin analogue, LIT-01-144, induces potent non-opioid peripheral antinociception in persistent pain via activation of GALR2

Yann Berthomé, Glenn-Marie Le Coz, Valérie Utard…·Frédéric Simonin

This study develops a spexin analog, LIT-01-144, that activates GALR2 to provide potent non-opioid antinociception in persistent pain without central nervous system penetration.

DOI 10.64898/2026.02.19.706558

mouseexperimental assay

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