Luke G. O’Neal

The B. subtilis translesion polymerase Pol Y1 is not strongly recruited to sites of replication upon different types of DNA damage

This study investigates the recruitment of Pol Y1, a TLS polymerase in B. subtilis, to replication sites under various DNA damage conditions and finds it is not strongly recruited upon damage.

The B. subtilis replicative polymerases bind the sliding clamp with different strengths to tune replication processivity and fidelity

This study investigates how the sliding clamp interacts with two replicative polymerases in B. subtilis, showing that PolC-DnaN binding is essential for replication while DnaE-DnaN interaction is dispensable but affects mutagenesis.