Author

Nicholas Sawyer

Fordham UniversityORCID 0000-0002-6393-5626Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Elizabeth S. ThralliD· 2 shared Sarah J. RanciciD· 2 shared Alyssa P. Campbell· 1 shared Ashley F. Clemente· 1 shared Emily E. Holmes· 1 shared Katrin M. KlasseniD· 1 shared Lindsey E. WayiD· 1 shared Luke G. O’NealiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBiochemistry

Elizabeth S. ThrallORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintMay 30, 2026

Characterizing the Molecular Determinants of Clamp Binding in B. subtilis

Sarah J. Rancic, Katrin M. Klassen, Nicholas Sawyer, Elizabeth S. Thrall

This study compares clamp binding in Escherichia coli and Bacillus subtilis, finding similar and distinct interactions between clamps and pentapeptide/hexapeptide motifs.

DOI 10.64898/2026.05.27.728225

E. colibacteria (other)

𝕏 PostBluesky

BiochemistrybioRxivPreprintMar 10, 2025

The B. subtilis replicative polymerases bind the sliding clamp with different strengths to tune replication processivity and fidelity

Luke G. O’Neal, Madeline N. Drucker, Ngoc Khanh Lai…·Elizabeth S. Thrall

This study investigates how the sliding clamp interacts with two replicative polymerases in B. subtilis, showing that PolC-DnaN binding is essential for replication while DnaE-DnaN interaction is dispensable but affects mutagenesis.

DOI 10.1101/2025.03.10.642433

bacteria (other)experimental assay

𝕏 PostBluesky