Michelle C.R. Yong

This paper combines evolutionary algorithms with AI to design potent Nectin-4-specific cancer biologics, achieving high-affinity minibinders and functional reagents.

This study examines neutrophil infiltration patterns in lymph nodes during adoptive T cell therapy in mice, revealing differences between tumor-draining and non-tumor-draining lymph nodes.

The paper identifies NKG7 as a reliable and consistent marker of cytotoxicity across immune subsets and tissues, outperforming traditional markers like Granzyme B and Perforin.

This paper develops AI-designed protein binders for cancer cell surface proteins, showing their effectiveness in detection and targeting through experimental validation and benchmarking of structure prediction models.