Author

Éléonore Bettacchioli

InsermORCID 0009-0002-0797-8098Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 2 Research Focus:batch correction / integration· 1 Approach:benchmark study· 1

Frequent Co-Authors

Marta Eugenia Alarcón-RiquelmeiD· 3 shared Anne BordroniD· 2 shared Cristian IperiiD· 2 shared Divi CorneciD· 2 shared Guillermo BartureniD· 2 shared Jacques‐Olivier PersiD· 2 shared A. R. Rekha· 1 shared Akhiya A.RiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersImmunology

Marta Eugenia Alarcón-RiquelmeORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

AltraFlowSOM: A Semi-Supervised Framework for Imaging Mass Cytometry Phenotyping

Akhiya A.R, Éléonore Bettacchioli, Christelle Le Dantec, Patrice Hémon, P Jouve, Sophie Hillion

AltraFlowSOM improves IMC phenotyping by combining semi-supervised learning with self-organizing maps, outperforming unsupervised and supervised methods in clustering and rare population detection.

bioRxiv · Sep 4, 2026 · PreprintBioinformatics

Interferon-α-Driven Stratification of B Cell Reveals Metabolic Reprogramming of Double Negative, Naive and Transitional cell subsets and Refines Molecular Classification in Söjgren's Disease.

Cristian Iperi, A. R. Rekha, Gustav Arvidsson, Gunnel Nordmark, Éléonore Bettacchioli, Marie Frutoso, Marta Eugenia Alarcón-Riquelme, Jessica Nordlund, Ann‐Christine Syvänen, Valérie Devauchelle‐Pensec, Divi Cornec, Sophie Hillon, Anne Bordron

This paper identifies an IFN-α signature in B cells of Sjögren's disease patients, revealing metabolic reprogramming and refining molecular classification.

European Journal of Immunology · Sep 1, 2026Peer-reviewedImmunology

Assessing the Molecular Validity of Spontaneous Lupus Mouse Models and Its Implication for Human Studies

María Rivas-Torrubia, Maria H. Morell, Zuzanna Makowska, Jorge Kageyama, Anne Bosshard, Julius Lindblom, María Orietta Borghi, Éléonore Bettacchioli, Ioannis Parodis, Lorenzo Beretta, Concepción Marañón, Jacques‐Olivier Pers, Ralf Lesche, Fiona McDonald, Marta Eugenia Alarcón-Riquelme, Guillermo Barturen

This study evaluates molecular pathways in four spontaneous lupus mouse models and compares them to human SLE to assess translational relevance and guide future research.

bioRxiv · May 15, 2025 · PreprintImmunology

BiomiX, a User-Friendly Bioinformatic Tool for Automatized Multiomics Data Analysis and Integration

Cristian Iperi, Álvaro Fernández‐Ochoa, Guillermo Barturen, Jacques‐Olivier Pers, Nathan Foulquier, Éléonore Bettacchioli, Marta Eugenia Alarcón-Riquelme, PRECISESADS Flow Cytometry Study Group, Divi Cornec, Anne Bordron, Christophe Jamin

BiomiX automates multiomics data analysis and integration, enabling efficient comparison of two cohorts through MOFA and providing interpretable results using literature and clinical data.

bioRxiv · Jun 14, 2024 · PreprintBioinformatics