ImmunologybioRxivPreprint
Antibody peptide epitope conjugates for αPD-1 therapy-resistant head and neck squamous cell carcinoma
Yifang Shui, David G. Millar, Lukas M. Altenburger…·Thorsten R. Mempel
This study develops antibody-peptide epitope conjugates (APECs) to enhance anti-tumor activity in ICB-resistant HNSCC by leveraging viral peptide-loaded MHC I proteins and protease activity.
DOI 10.64898/2025.11.28.691238