Author

Thomas Janas

Henry M. Jackson FoundationORCID 0009-0002-1984-2411Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Ayesha A. ShafiiD· 2 shared Christopher M. McNairiD· 2 shared Karen E. KnudseniD· 2 shared Lakshmi Ravindranath· 2 shared Xiaofeng A. SuiD· 2 shared Adam SharpiD· 1 shared Amina Ali· 1 shared Arwa FallatahiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Ayesha A. ShafiORCID

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 14, 2026

Bacterial vitamin sharing emerges from a balance between release and uptake

Freddy Bunbury, Thomas Janas, Paige A. Mullen…·Seppe Kuehn

The paper quantifies vitamin B12 synthesis and uptake in bacterial isolates, revealing strategies that govern extracellular B12 availability through a balance between release and uptake.

DOI 10.64898/2026.09.01.748612

bacteria (other)proteomics

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Cancer BiologybioRxivPreprintMay 21, 2026

Stage-Specific Regulation of DNA Damage Repair by the Circadian Regulator, CRY1, in Prostate Cancer

Arwa Fallatah, Stefan DiFazio, Lakshmi Ravindranath…·Ayesha A. Shafi

This study identifies CRY1 as a stage-specific regulator of DNA damage repair in prostate cancer, showing it promotes NHEJ/BER in hormone-sensitive disease and HR in castration-resistant disease.

DOI 10.64898/2026.05.19.726303

humanbulk RNA-seq

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Cancer BiologyOncogenePeer-reviewedSep 12, 2024

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer

Sumaira Sardar, Christopher M. McNair, Lakshmi Ravindranath…·Ayesha A. Shafi

This study identifies CBP/p300 as critical for DNA repair in prostate cancer and shows that targeting it enhances therapeutic response.

21 citations

humanbulk RNA-seq

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