ImmunologyScience AdvancesPeer-reviewed
Human Stem Cell-Derived β-cells Expressing An Optimized CD155 Reduce Cytotoxic Immune Cell Function for Application in Type 1 Diabetes
Matthew E. Brown, Jessie M. Barra, Mariana Pina…·Holger A. Russ
This study shows that human stem cell-derived β-cells expressing a high-affinity CD155 variant reduce immune cell cytotoxicity, improving their potential for type 1 diabetes therapy.
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