Cell BiologyThe CRISPR JournalPeer-reviewed
Efficient installation of heterozygous mutations in human pluripotent stem cells using prime editing
Annabelle Suter, Alison N. Graham, Jia Yi Kuah…·Sara E. Howden
This study demonstrates the use of prime editing to efficiently introduce heterozygous mutations in human pluripotent stem cells with high knock-in efficiency and without purification or selection steps.
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