Author

Connor Macfarlane

Mary Lyon Centre at MRC HarwellORCID 0009-0002-2624-8955Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Adam CaulderiD· 1 shared Anthony R IslesiD· 1 shared Gemma F. CodneriD· 1 shared Jade DesjardinsiD· 1 shared Karen J. LiuiD· 1 shared Lydia TebouliD· 1 shared Matthew MackenzieiD· 1 shared Michelle E. StewartiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Adam CaulderORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintMay 7, 2026

Combining Cas9 and dCas9 facilitates genome editing in genes associated with viability or welfare issues, or within paralogous gene clusters

Skevoulla Christou, Connor Macfarlane, Adam Caulder…·Lydia Teboul

This study shows that combining dCas9 and Cas9 improves viability and reduces off-target effects when editing genes linked to viability or paralogous clusters.

1 citation

mouseCRISPR screen

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