Author

Patricia Reist Iscar

University of BaselORCID 0009-0002-2715-6710Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Hoi Ching CheungiD· 2 shared Marek BasleriD· 2 shared Miro Thorsten Wilhelm PlumiD· 2 shared Daria Jacqueline Wüst· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersMicrobiology

Hoi Ching CheungORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintAug 24, 2026

Intranuclear niche: actin-tail mediated nuclear entry by intracellular pathogens

Hoi Ching Cheung, Patricia Reist Iscar, Miro Thorsten Wilhelm Plum, Marek Basler

This study shows that intracellular pathogens like Burkholderia thailandensis and Shigella flexneri can enter host nuclei via actin tail motility, forming a protective niche in mitotically active cells.

DOI 10.64898/2026.08.23.746248

humanmouse

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MicrobiologybioRxivPreprintJan 30, 2026

Regulation of Type VI secretion systems of Burkholderia thailandensis during transition to intracellular lifestyle

Hoi Ching Cheung, Daria Jacqueline Wüst, Miro Thorsten Wilhelm Plum…·Marek Basler

This study shows Burkholderia thailandensis switches from T6SS-1 to T6SS-5 during phagosomal maturation, controlled by the VirAG two-component system.

DOI 10.64898/2026.01.30.702787

bacteria (other)experimental assay

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