Author

Nicolas Lewerenz

University of BaselORCID 0009-0002-2738-7535Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Jacek StępniewskiiD· 1 shared Józef DulakiD· 1 shared Judith R. ReinhardiD· 1 shared Krzysztof SzadeiD· 1 shared Markus A. RüeggiD· 1 shared Marta BiałobrzeskaiD· 1 shared Shuo Lin· 1 shared Timothy J. McGowaniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperMolecular Biology

Jacek StępniewskiORCID

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1 paper

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedNov 27, 2025

Loss of cell-autonomously secreted laminin-α2 drives muscle stem cell dysfunction in LAMA2-related muscular dystrophy

Timothy J. McGowan, Judith R. Reinhard, Nicolas Lewerenz…·Markus A. Rüegg

This study shows that laminin-α2 secreted by muscle stem cells is critical for their expansion and regeneration, and its loss leads to muscle stem cell dysfunction in LAMA2-related muscular dystrophy.

6 citations

humanbulk RNA-seq

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