Author

Jan Georg Gerstenberger

Leibniz University HannoverORCID 0009-0002-2932-3113Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:experimental assay· 1 Research Focus:phylogenetics / evolution· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Colin Schür· 1 shared Elske van der PoliD· 1 shared Gyula HoffkaiD· 1 shared Klaus Peter SchliepiD· 1 shared Lisa-Marie KrammeriD· 1 shared Robert KouristiD· 1 shared Selin KaraiD· 1 shared Shina Caroline Lynn KamerliniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

Colin Schür

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1 paper

Recent·Most cited

Ancestors of Arylmalonate Decarboxylase show increased Activity, Stability and Stereoselectivity

Elske van der Pol, Jan Georg Gerstenberger, Xenia Georgiadou, Gyula Hoffka, Lisa-Marie Krammer, Klaus Peter Schliep, Colin Schür, Shina Caroline Lynn Kamerlin, Selin Kara, Robert Kourist

Ancestral sequence reconstruction of a bacterial decarboxylase gave enzymes with up to 294-fold longer half-life at 45 °C, higher activity, and 99.7% ee on a vinyl malonate substrate.

bioRxiv · Aug 20, 2026 · PreprintBiochemistry✦ In-depth digest