Molecular BiologybioRxivPreprint
Chitinase-3-like protein 1 decodes chitosan acetylation patterns into toll-like receptor 2 signaling through heparan sulfate
Alexandra Großdorf, Sina Nabil, Carlotta Imelmann…·Christian Gorzelanny
This study shows CHI3L1 interacts with chitosan and heparan sulfate to activate TLR2 signaling, revealing HS as a co-receptor for CHI3L1 and its role in inflammation.
2 citations