Bruno Maria Moerschbacher

This study shows that chitin oligomers of specific lengths activate the NLRP3 inflammasome and induce innate immune training through phagocytosis and methyl transferase activity.

The paper assesses the biological activity of RNA-based crop protection formulations in plants and non-target organisms, finding low activity across tested systems.

This study shows CHI3L1 interacts with chitosan and heparan sulfate to activate TLR2 signaling, revealing HS as a co-receptor for CHI3L1 and its role in inflammation.

The paper produces chitosan oligomers using chitosanase enzymes to enhance plant resistance to viral infection, finding that higher DP increases efficacy.

The paper investigates the structural and chemical properties of chitin in insect extracellular matrices, finding that PM chitin is highly acetylated and organized as dihydrate β-chitin, while cuticle chitin is deacetylated and structured as α-chitin.

This paper shows how domain gain or loss in fungal chitinases determines their function as either antimicrobial or immune-suppressive effectors.