Author

Thomas Sontag

Centre Hospitalier Universitaire Sainte-JustineORCID 0009-0002-3510-7804Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1

Frequent Co-Authors

Daniel SinnettiD· 2 shared Sonia CellotiD· 2 shared Sylvie Langlois· 2 shared Thai Hoa TraniD· 2 shared Vincent‐Philippe LavalléeiD· 2 shared Alex Richard-St-HilaireiD· 1 shared Alexandre RouetteiD· 1 shared Arnaud DroitiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Daniel SinnettORCID

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2 papers

Recent·Most cited

Unveiling the temporal impact: Exploring dynamic changes in the paediatric solid tumour immune microenvironment through time

Virgile Raufaste-Cazavieille, Stéphanie Bianco, Lara Herrmann, Jeyani George Clement, Emeric Texeraud, Sylvie Langlois, Thomas Sontag, Pascal Tremblay-Dauphinais, Alex Richard-St-Hilaire, Charles Joly Beauparlant, Damien Faury, Stéphanie Vairy, Nada Jabado, Sonia Cellot, Vincent‐Philippe Lavallée, , Raoul Santiago

This study examines the dynamic changes in the immune microenvironment of paediatric solid tumours over time, revealing a shift toward immunosuppressive and tolerogenic states.

bioRxiv · Oct 7, 2025 · PreprintCancer Biology

Real-time molecular classification of leukemias

Mélanie Sagniez, Shawn M. Simpson, Maxime Caron, Marieke J. Rozendaal, Bastien Paré, Thomas Sontag, Sylvie Langlois, Alexandre Rouette, Vincent‐Philippe Lavallée, Sonia Cellot, Daniel Sinnett, Thai Hoa Tran, Martin A. Smith

This study demonstrates real-time transcriptomic profiling using nanopore sequencing and a neural network classifier to classify childhood acute lymphoblastic leukemia subtypes efficiently.

medRxiv · Jun 22, 2022 · PreprintGenetic & Genomic Medicine