Author

Sylvie Langlois

Centre Hospitalier Universitaire Sainte-Justine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Daniel SinnettiD· 3 shared Thai Hoa TraniD· 3 shared Maxime CaroniD· 2 shared Sonia CellotiD· 2 shared Thomas SontagiD· 2 shared Vincent‐Philippe LavalléeiD· 2 shared Adam S. FischiD· 1 shared Alex Richard-St-HilaireiD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Daniel SinnettORCID

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3 papers

Recent·Most cited

Unveiling the temporal impact: Exploring dynamic changes in the paediatric solid tumour immune microenvironment through time

Virgile Raufaste-Cazavieille, Stéphanie Bianco, Lara Herrmann, Jeyani George Clement, Emeric Texeraud, Sylvie Langlois, Thomas Sontag, Pascal Tremblay-Dauphinais, Alex Richard-St-Hilaire, Charles Joly Beauparlant, Damien Faury, Stéphanie Vairy, Nada Jabado, Sonia Cellot, Vincent‐Philippe Lavallée, , Raoul Santiago

This study examines the dynamic changes in the immune microenvironment of paediatric solid tumours over time, revealing a shift toward immunosuppressive and tolerogenic states.

bioRxiv · Oct 7, 2025 · PreprintCancer Biology

Outlier expression of isoforms by targeted RNA sequencing as clinical markers of genomic variants in B lymphoblastic leukemia and other tumor types

Harrison Kwei Tsai, Tasos Gogakos, Va Lip, Jonathan M. Tsai, Yen-Der Li, Adam S. Fisch, Jonathan Weiss, Leslie Grimmett, Thai Hoa Tran, Maxime Caron, Sylvie Langlois, Daniel Sinnett, Yana Pikman, Annette S. Kim, Valentina Nardi, , Marian H. Harris

The paper identifies outlier RNA isoform expression as a method to detect clinically relevant genomic variants in B-ALL and other cancers with high sensitivity and specificity.

medRxiv · Jul 29, 2022 · PreprintGenetic & Genomic Medicine

Real-time molecular classification of leukemias

Mélanie Sagniez, Shawn M. Simpson, Maxime Caron, Marieke J. Rozendaal, Bastien Paré, Thomas Sontag, Sylvie Langlois, Alexandre Rouette, Vincent‐Philippe Lavallée, Sonia Cellot, Daniel Sinnett, Thai Hoa Tran, Martin A. Smith

This study demonstrates real-time transcriptomic profiling using nanopore sequencing and a neural network classifier to classify childhood acute lymphoblastic leukemia subtypes efficiently.

medRxiv · Jun 22, 2022 · PreprintGenetic & Genomic Medicine