Author

C. A. Meredith

Howard Hughes Medical InstituteORCID 0009-0002-4597-3239Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Jennifer A. DoudnaiD· 2 shared Agni RajinikanthiD· 1 shared Arushi LahiriiD· 1 shared Benjamin A. AdleriD· 1 shared Claire E O'BrieniD· 1 shared Conner J. LangebergiD· 1 shared Dimple Amitha Garuadapuri· 1 shared Erin E. DohertyiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioinformatics

Jennifer A. DoudnaORCID

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2 papers

Recent·Most cited

Improving RNA Secondary Structure Prediction Through Expanded Training Data

Conner J. Langeberg, Taehan Kim, Roma Nagle, Agni Rajinikanth, C. A. Meredith, Dimple Amitha Garuadapuri, Jennifer A. Doudna, Jamie H. D. Cate

The paper improves RNA secondary structure prediction by training a deep learning model on a new dataset of RNA sequences and structures, showing better generalization to unseen RNA families.

RNA · Sep 1, 2026Peer-reviewedBioinformatics

Recurrent acquisition of nuclease-protease pairs in antiviral immunity

Owen T. Tuck, Jason J. Hu, Santiago C. Lopez, Benjamin A. Adler, Claire E O'Brien, Kendall Hsieh, Charlotte Meredith, Kenneth J. Loi, Peter H. Yoon, Erin E. Doherty, Arushi Lahiri, Jennifer A. Doudna

The paper identifies recurrent acquisition of nuclease-protease pairs in bacterial antiviral immunity and shows their proteolytic activation mechanism across different immune systems.

Science · Nov 13, 2025Peer-reviewedMicrobiology