Author

Pauline M. Wijers‐Koster

Leiden University Medical CenterORCID 0009-0002-4758-7016Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Debora M. MeijeriD· 2 shared Inge H. Briaire‐de BruijniD· 2 shared Judith V.M.G. BovéeiD· 2 shared Michiel A. J. van de SandeiD· 2 shared Noel F.C.C. de MirandaiD· 2 shared Anne‐Marie Cleton-JanseniD· 1 shared Anouk A. KruiswijkiD· 1 shared Brendy E.W.M. van den Akker· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Debora M. MeijerORCID

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2 papers

Recent·Most cited

Divergent Therapeutic and Prognostic Impacts of Immunogenic Features in Undifferentiated Soft Tissue Sarcoma and Myxofibrosarcoma

Siddh van Oost, Debora M. Meijer, Zeynep Betül Erdem, Marieke E. Ijsselsteijn, Jessica P Roelands, Suk Wai Lam, Melissa Suraya Boejharat, Brendy E.W.M. van den Akker, Ruud van der Breggen, Inge H. Briaire‐de Bruijn, Lukas J.A.C. Hawinkels, Anouk A. Kruiswijk, Manon van der Ploeg, Pauline M. Wijers‐Koster, Rick L. Haas, , Judith V.M.G. Bovée

This study compares immunogenic features between undifferentiated soft tissue sarcoma and myxofibrosarcoma, finding differences in T cell and macrophage infiltration and their prognostic significance.

Cancer Immunology Immunotherapy · Jul 2, 2025Peer-reviewedCancer Biology

The variable genomic landscape during osteosarcoma progression: insights from a longitudinal WGS analysis

Debora M. Meijer, Dina Ruano, Inge H. Briaire‐de Bruijn, Pauline M. Wijers‐Koster, Michiel A. J. van de Sande, Hans A. J. Gelderblom, Anne‐Marie Cleton-Jansen, Noel F.C.C. de Miranda, Marieke L. Kuijjer, Judith V.M.G. Bovée

This study analyzes the genomic changes in osteosarcoma over time using WGS, revealing increasing genomic complexity and variable evolutionary patterns.

Genes Chromosomes and Cancer · Jul 1, 2024Peer-reviewedGenetic & Genomic Medicine