Lisa Young

This paper shows that IL-1-activated cancer-associated fibroblasts (iCAFs) promote STAT1-driven transcriptional reprogramming in pancreatic tumour cells, leading to chemoresistance and identifying STAT1 as a therapeutic target.

This study uses multi-scale photoacoustic imaging to identify biomarkers of radiation therapy response in breast cancer models, showing improved outcomes with denser vasculature and increased oxygen saturation.