Author

Barbara Gruenwald

Essen University Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Abigail R. EdwardsiD· 1 shared Alasdair Russell· 1 shared Catarina PelicanoiD· 1 shared Chandra Sekhar Reddy ChilamakuriiD· 1 shared Clive S. D’SantosiD· 1 shared Elizabeth Mannion· 1 shared Evangelia K. PapachristouiD· 1 shared Giulia BiffiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Abigail R. EdwardsORCID

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Author profile →

1 paper

Recent·Most cited

IL-1-activated cancer-associated fibroblasts promote STAT1-driven transcriptional reprogramming of pancreatic tumour cells

Catarina Pelicano, Igor V. Chernukhin, Marleen Woelke, Priscilla S.W. Cheng, Lisa Young, Abigail R. Edwards, Elizabeth Mannion, Yi Cheng, Maureen Crowshaw, Steven Kupczak, Sara Pinto Teles, Muntadher Jihad, Kamal Kishore, Chandra Sekhar Reddy Chilamakuri, Valar Nila Roamio Franklin, , Shalini V. Rao

This paper shows that IL-1-activated cancer-associated fibroblasts (iCAFs) promote STAT1-driven transcriptional reprogramming in pancreatic tumour cells, leading to chemoresistance and identifying STAT1 as a therapeutic target.

bioRxiv · May 29, 2026 · PreprintCancer Biology