Chandra Sekhar Reddy Chilamakuri

This paper shows that IL-1-activated cancer-associated fibroblasts (iCAFs) promote STAT1-driven transcriptional reprogramming in pancreatic tumour cells, leading to chemoresistance and identifying STAT1 as a therapeutic target.

This study identifies MOZ and HBO1 as molecular dependencies in NUP98-rearranged AML, showing their inhibition reduces leukemic burden and synergizes with Menin inhibitors.

The paper investigates how PTEN and ARID1A haploinsufficiency in colonic epithelium contributes to oncogenic transformation by altering clone dynamics and creating a pro-tumorigenic microenvironment.

GenEditID is a platform for identifying CRISPR-edited cell clones using deep sequencing and proteomic data, enabling scalable and sensitive gene editing analysis.