Inhibition of Renin Release, a Crucial Event in Homeostasis, is Mediated by Coordinated Calcium Oscillations within Juxtaglomerular Cell Clusters.
Hiroki Yamaguchi, Nick A. Guagliardo, Laura A. Bell, Manako Yamaguchi, Daisuke Matsuoka, Fang Xu, Jason P. Smith, Mohamed Diagne, Sophie Condron, Lucas Ferreira de Almeida, Silvia Medrano, Paula Q. Barrett, Edward H. Nieh, R. Ariel Gómez, Maria Luisa S. Sequeira-Lόpez
This study investigates how AngII inhibits renin release in JG cell clusters through coordinated calcium oscillations, identifying key cellular mechanisms involved.
Circulation Research · Sep 3, 2025Peer-reviewedCell Biology