Cancer BiologyNeoplasiaPeer-reviewed
The DNA Mismatch repair protein, MSH6 is a novel regulator of PD-L1 expression
Kirsten Brooksbank, Charlotte Smith, Eleni Maniati…·Sarah A. Martin
The paper shows that MSH6 regulates PD-L1 expression through SETD2 recruitment, and MSH6 KO cells have lower microsatellite instability despite higher mutational burden compared to MLH1 KO cells.
2 citations